The No. One Question That Everyone Working In BNSF Railway Lung Cancer Should Know How To Answer > 자유게시판

Acute Lymphocytic Leukemia

A colorless, flammable liquid with the scent of sweets in the air, benzene is a principal cause of leukemia. Railroad workers have for a long time been exposed to benzene by exhaust from diesel engines and as a constituent in creosote, coal tar distillates, naphtha, carbolineum as well as other cleaning solvents.

The treatment for acute lymphocytic leukemia can last anywhere from two to three years. It consists of Remission-induction therapy in addition to consolidation therapy and maintenance therapy. The palliative treatment is also an integral part of the treatment plan.

Symptoms

The signs and symptoms of leukemia refer to changes in the body when cancer cells begin to expand. These abnormal blood cells, also referred to Bnsf Railway Non Hodgkins Lymphoma or leukemia, grow up in the bone marrow, and crowd out healthy blood cells which makes it difficult for the body to fight infection, stop bleeding, as well as provide oxygen to the rest of the body's cells. Acute Lymphocytic Leukemia (ALL) is a form of blood cancer that starts in the immature white blood cells in the bone marrow, which is the hollow space within bones that is where blood is made.

The DNA of the bone-marrow cell undergoes mutations which result in the cell growing and divide at a higher rate than normal. The cancerous cells invade the bone marrow and hinder the production of new blood cells.

These symptoms may include the loss of appetite, fever weight loss and vomiting, fatigue, and enlarged lymph nodes. If the central nervous system is involved the patient may experience headaches, seizures or vision problems.

It is known that Benzene can cause Leukemia and other blood disorders in railroad workers. Benzene is present in the solvents used in railroads and is present in the diesel fuel that powers locomotives. Even low levels of exposure for a long period of time could be harmful.

Diagnosis

The disease is characterised by abnormal white blood cells, also known as lymphocytes, which cause the bone marrow to produce too many leukemia-related cells, and not enough healthy ones. The term "acute" refers to cancer that is rapidly growing and affects immature cells. The cancer affects the production and distribution of the new white and red blood cells.

In certain cases, symptoms could include fever, night sweats and weight loss. Other symptoms may include swollen lymph nodes or glands, bone pain, or the hepatosplenomegaly. These symptoms are similar to those experienced by the flu, therefore they are difficult to identify.

Doctors use a variety of tests and procedures for diagnosing the condition. These include blood tests that determine the amount and type of the body's chemical composition. They also conduct a spinal fluid (lumbar puncture) and a bone-marrow analysis and imaging tests.

Induction therapy is the first stage of treatment. The goal is to kill the leukemia-causing cell and restore normal blood cell production. The aim is to bring the cancer into an end-of-life.

Treatment

The majority of patients with ALL experience a complete reaction to treatment, which means the leukemia cells have gone from bone marrow and blood. However tiny amounts of leukemia may persist even after treatment. These tiny amounts of Leukemia, known as minimal residual disease (MRD) can be detected using methods that aid doctors determine if further treatment is needed.

The most effective treatment for ALL is chemotherapy. Induction chemotherapy is typically the first treatment. It destroys the majority of leukemia cells. After that, doctors might prescribe consolidation therapy to destroy any remaining leukemia cells and to stop the growth of these cells. They can also inject chemotherapy drugs directly into cerebrospinal liquid (CSF) which is the fluid that surrounds the spinal cord and brain. This is known as intrathecal therapy and it is based on the medications methotrexate or cytarabine along with the steroid prednisone.

Doctors can often bring leukemia back into remission by introducing more chemotherapy if it recurs after treatment. It is more likely, however, bnsf railway non Hodgkins lymphoma that the remission will not be permanent and that the cancer will be recurred at some point. Certain individuals with ALL suffer from an abnormality in the genetic code known as the Philadelphia chromosome. They are treated differently than other ALL patients. They may receive specialized chemotherapy that targets specific genetic mutations that are found in their leukemia. This type of treatment may be more harmful and the cure rate for these patients is lower than that of those who don't have this chromosome change.

Prognosis

A variety of factors influence the prognosis of patients with this type of cancer. Certain groups are more likely to be affected than others, such as those who suffer from a genetic disorder or who have been exposed to toxins. Different types of leukemia also have different rates of survival.

The disease is caused by errors in the DNA of bone-marrow cells. These errors, called mutations, cause cells to expand faster than normal and to encircle healthy cells in the process. The leukemia cells are in a position to function properly and could be unable to fight infection.

A few people suffering from this disease also have a genetic defect called the Philadelphia chromosome. This can result in an aggressive form of disease. Penn medical oncologists, hematologists and other specialists can provide specific treatments that are adapted to the genetic makeup of this kind of leukemia.

Because of their exposure to hazardous chemicals and bnsf railway non Hodgkins lymphoma substances, railroad workers are more likely to develop the condition. Many of them are diagnosed with cancers, like mesothelioma, or acute myeloid lymphoma (AML). Railroad workers have been exposed for a long time to benzene. This clear liquid with a pleasant smell is used as a solvent and also in diesel exhaust.