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Multiple Myeloma and the Kansas City Southern Railway Asthma kansas city southern railway mds kansas city southern railway colon cancer kansas city southern railway pancreatic cancer

Diesel exhaust is one of the many hazardous chemicals railroad workers are exposed to. They could develop kansas city southern railway stomach cancer or other health problems due to this exposure.

Myeloma is a kind of blood cancer that affects plasma cells that are found in the bone marrow. They make antibodies. It can cause swelling, pain and other signs.

What is Multiple Myeloma?

Multiple myeloma is a cancer of plasma cells, which make up a part of the immune system. Plasma cells produce antibodies that aid the immune system fight infection. They are mostly found in bone marrow, the soft sponge-like tissues that produce blood inside each bone. Multiple myeloma begins in plasma cells found in the bone marrow, and then spreads to other tissues, including the kidneys and the spinal cord.

In multiple myeloma, the cancerous plasma cells produce abnormal antibodies which gather in the kidneys and other organs, forming a mass referred to as a tumor. These masses can be one cell, or they may be clusters of cells. The tumors or lesions can cause various symptoms and signs, such as fatigue, weakness bones, pain in the knees and a burning sensation in the arms and legs. They can also cause anemia, hypercalcaemia and problems with bones.

Multiple myeloma has no known reason, but certain factors can increase the likelihood of a person being diagnosed with it. The most common factors are age (most people with myeloma have reached 60 years old, and the disease affects blacks twice as many as white people) and the presence of monoclonal-gammopathy, or myelodysplastic syndrome. People who have been exposed to radiation or certain chemicals such as pesticides or benzene are at increased risk.

What do I know if Multiple Myeloma Diagnosed?

In its early stages of the disease, multiple myeloma might not cause any symptoms. It is often only suspected or diagnosed after an examination of urine or blood. Your GP will check your back, hips and ribs. This is called a skeletal survey and may be an important first step. You may also be asked if are experiencing other symptoms, such as tiredness and a decrease in appetite or bruising more frequently than normal (a indication that plasma cells are hindering your body from producing enough platelets to stop bleeding).

Your doctor will test fluid around the lung for paraprotein. They will also examine your blood and a sample of your bone marrow to look for abnormal proteins made by myeloma cells. Your GP might recommend you to a haematologist (a specialist doctor who is specialized in conditions that affect blood) for further tests and scans.

X-rays and magnetic resonance imaging (MRI) and a computed Tomography (CT) scan can help identify damage to the bones caused by myeloma. Other tests include a PET scan, a positron emission (PET) and FDG scan, which can help in identifying areas with cancerous plasma cells. Plasma exchange therapy (plasmapheresis) eliminates the abnormal protein from your body and may reduce its effects on the eyes, kidneys and nerves.

What is the Treatment for Multiple Myeloma

Typically, symptoms of multiple myeloma improve with treatment. The blood test should be checked monthly for CRAB characteristics (Calcium levels Renal/Kidney function and anemia and Bone health) and also any needed imaging scans like X-rays, Kansas City Southern Railway Asthma or MRIs.

As an induction and maintenance treatment, a majority of patients will receive a combination of drugs. This includes dexamethasone and lenalidomide and an antibody monoclonal, like elotuzumab (Empliciti) or daratumumab (Darzalex), that is attached to carfilzomib or pomalidomide.

These medications slow down the growth of myeloma. They can be taken by pill or through vein. Some people also take bortezomib which is one of the forms of Velcade. This drug is sometimes combined with lenalidomide and dexamethasone as well as doxorubicin cyclophosphamide.

Surgery is not a cure for multiple myeloma. However it is a method to relieve certain symptoms like spinal compression (from fractured vertebrae or plasmacytoma), or to remove large tumors which interfere with breathing.

The treatment for cancer can cause physical side-effects, like pain. They can also have social and emotional consequences. Managing these side effects is called palliative treatment and is an essential component of your overall treatment plan. Your treatment team may include the general practitioner, a hemologist (a specialist in the diagnosis and treatment of diseases of the blood) as well as radiation oncologists, cancer nurse, dietitian and/or a pain management expert.

What are the side effects of Multiple Myeloma Treatments?

Many of the medications used to treat myeloma cause negative side effects. The severity and nature of side effects will depend on the chemo drugs that you are taking and your health prior to treatment, and your personal reaction. In this video, hematologist-oncologist Adriana Rossi describes some of the side effects of common therapies for multiple myeloma.

Chemotherapy for multiple myeloma generally includes a variety of drugs in a a chemotherapy regimen. The chemo drugs kill cancerous cells. Steroids, for instance, can be added to chemotherapy regimens to increase the probability of a positive result, or reduce the amount of chemo needed. Steroids can trigger side effects like hyperglycemia, diarrhea, and changes in appetite.

Your medical team will create your treatment plan based on your test results and the stage of kansas city southern railway colon cancer, symptoms, and overall health. Your healthcare team will discuss with you whether or not you would prefer to be part of a clinical study that tests a new drug or a combination of conventional treatment options.

Although it isn't possible to treat myeloma multiplex treatment is a great way to manage symptoms and prolong your life. Your care team will work with you to develop an approach to manage your discomfort, side effects, and other symptoms so you can live your life to the fullest. Palliative care is.

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