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작성자 Lawrence
댓글 댓글 0건   조회Hit 31회   작성일Date 23-06-05 03:16

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Multiple Myeloma and csx transportation esophageal cancer Transportation

Peter worked for the Long Island Railroad Company for 29 years. Through that time Peter was exposed to a number of hazardous chemicals. These chemicals and substances included creosote and diesel fumes.

Multiple myeloma is a disease that affects the plasma cells that make antibodies to fight disease and infections. The cancerous cells create bone tumors known as plasmacytomas.

Symptoms

The cancer attacks the plasma cells that create antibodies to aid the body in fighting germs and infections. Multiple myeloma symptoms include back pain and the ribs. It also causes brittle bones that break easily weakening, fatigue and loss of appetite and kidney issues.

Most of the time, myeloma doesn't cause symptoms in its initial stages. A doctor may not discover it until the routine urine or blood test for a different condition is found to have higher levels of proteins than normal. This is known as myeloma that has smoldering symptoms. In the latter stages, myeloma could cause damage to organs like the kidneys or lungs, as well as the nervous system, which can cause issues with balance and vision.

Your outlook depends on the stage of myeloma, other health conditions you have, and your age when diagnosed. Your prognosis is also dependent on the number of plasma cells that develop tumors and cause complications, as well genetic factors that impact the likelihood of developing myeloma.

People who have a chromosomal defect called deletion 17p or duplication 18q face a more difficult chance of surviving than people who don't have these conditions. Kidney function is also crucial in that if your kidneys aren't working as well, Csx Transportation Stomach Cancer you are more likely to be in a worse position. The amount of creatinine in your blood is a good indicator of how your kidneys are working.

Diagnosis

Multiple myeloma gets diagnosed when a person's blood or urine is tested for another illness and more than the normal amount of protein is observed. Myeloma symptoms include bone pain, bone weakness (including the back and ribs) kidney problems and a fever with no known cause, bruising or difficult breathing.

The disease is more common among people over the age of 60 and is most commonly seen by men over the age of 60. People with a first-degree family member who has myeloma have about a 2 to 3 times higher chance of being diagnosed than the rest of us. This includes parents, siblings and children.

There are a number of risk factors for myeloma. These include a prior diagnosis of solitary plasmacytoma of the bone or an extramedullary blood clot in soft tissue (such as the lung or throat). People who have been exposed to radiation or certain chemicals, such as asbestos, benzene and pesticides are at greater risk of developing myeloma. Myeloma is also more prevalent in those with an elevated monoclonal-gammopathy of undetermined significance (MGUS).

The experts of the plaintiffs' were two toxicologists and an epidemiologist. Toxicology is the discipline which studies the ways in which a chemical could be harmful and how exposure could cause the development of a disease. Epidemiology examines the causes and effects of exposure to chemicals, such as those caused by myeloma. This is done by examining medical records and statistics.

Treatment

Myeloma treatment is centered around radiation and chemotherapy. There are a variety of chemotherapy drugs available. There is a brand new class known as monoclonal antibodies, which can destroy myeloma cell. These include daratumumab and Csx transportation stomach cancer elotuzumab. Combining these therapies with other treatments improves the outcome. Other treatments involve transplants, stem cell therapies, immunotherapies and cell-based vaccines.

While myeloma is a disease that affects people of any age, certain factors increase the likelihood of developing the disease. Those who are older than 45 have a higher risk and those who have an extended family history of myeloma. People who have been exposed to radiation or chemical exposure are also at greater risk. This includes workers who have been exposed to X-rays as well as those who worked in industries that use asbestos, benzene, and herbicides like Agent Orange.

Ronald Harris died in 2013 from multiple myeloma. His estate filed a lawsuit against CSX Transportation claiming that his work as a railroad employee led to the development of his cancer. The trial court held an evidentiary hearing to listen to the testimony of three plaintiffs' scientific experts: Dr. Goldstein and Dr. Infante. They used proven methods to establish that the diesel exhaust fumes emitted by Csx Transportation Stomach Cancer resulted in Harris myeloma. The testimony of the expert witness was based on studies of human subjects as well as animal studies in relation to the chemical composition and closely related pyrogenic material of diesel exhaust, and experiments with B lymphocytes.

Prognosis

Multiple myeloma can affect plasma cells. These cells are vital to the immune system because they aid in the body's fight off diseases and infections. When someone is diagnosed with myeloma plasma cells start to grow out of control and take over normal bone marrow. This can lead to other health issues, including low blood counts as well as bone damage.

Multiple myeloma is more likely to develop in those who have many risk factors. This includes age, family history, and exposure to radiation or certain chemicals. A first-degree relative with multiple myeloma is twice as likely to get it by themselves. Myeloma is also more prevalent in black people than white people.

Ronald Harris was a railroad trainman for csx transportation interstitial lung disease Transportation. He worked there for 29 years. He was exposed every day to diesel exhaust from locomotives. Harris developed multiple myeloma during his time at. The cancer attacks plasma cells within the bone marrow. Harris brought a lawsuit under the Federal Employers' Liability Act and Locomotive Inspection Act against csx transportation scleroderma. Unfortunately, Harris died while the case was in the midst of being resolved. His wife, Deborah Kay Harris, was appointed as plaintiff.

Petitioner retained Dr. Peter Shields and Dr. Laura Green as expert witnesses in the trial. During the two-day hearing both experts presented their backgrounds and the method that they used to express their opinions. Both experts rely on the Bradford Hill methodology.

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